Impact of Tenofovir on Hepatitis Delta Virus Replication in the Swiss Human Immunodeficiency Virus Cohort Study.

Béguelin, Charles; Friolet, Nicole; Moradpour, Darius; Sahli, Roland; Suter-Riniker, Franziska; Lüthi, Alexander; Cavassini, Matthias; Günthard, Huldrych F et al. · Clin Infect Dis · 2017

retrospective_cohort · Level III

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Abstract

We analyzed changes in hepatitis B virus and hepatitis delta virus (HDV) viral loads (VL) during tenofovir-containing antiretroviral therapy among patients with a replicating HDV infection in the Swiss HIV Cohort Study. Only 28.6% experienced a ≥2.0 log reduction in HDV RNA, and 14.3% had undetectable HDV VL within 5 years.

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