LASER server: ancestry tracing with genotypes or sequence reads.
other · Level V
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- Record sourced from PubMed, PMID 28200055.
- Also identified by DOI 10.1093/bioinformatics/btx075 and PMC identifier 5870850.
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Abstract
To enable direct comparison of ancestry background in different studies, we developed LASER to estimate individual ancestry by placing either sezquenced or genotyped samples in a common ancestry space, regardless of the sequencing strategy or genotyping array used to characterize each sample. Here we describe the LASER server to facilitate application of the method to a wide range of genetic studies. The server provides genetic ancestry estimation for different geographic regions and user-friendly interactive visualization of the results. The LASER server is freely accessible at http://laser.sph.umich.edu/. dtaliun@umich.edu or wangcl@gis.a-star.edu.sg. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Genetic Variation
- Phylogeography
- Population Groups
- Sequence Analysis, DNA
- Software