Mammalian Heart Regeneration: The Race to the Finish Line.

Doppler, Stefanie A; Deutsch, Marcus-Andre; Serpooshan, Vahid; Li, Guang; Dzilic, Elda; Lange, Rüdiger; Krane, Markus; Wu, Sean M · Circ Res · 2017

review · Level V

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Abstract

A long-standing goal of cardiovascular scientists is to repair damaged hearts following myocardial infarction by overcoming the limited regenerative capacity of the adult mammalian heart. A number of new strategies are being actively investigated for generating functional cardiomyocytes or progenitor cells. The race is on for the first demonstration of durable therapeutic heart repair in human.

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