Unveiling the Role of Senescence-Induced Cellular Plasticity.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28257706.
- Also identified by DOI 10.1016/j.stem.2017.02.001.
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Abstract
Mice expressing Yamanaka factors develop teratomas containing iPSCs, suggesting that somatic cells are reprogrammable in vivo. Recent studies in Cell, Science, and this issue of Cell Stem Cell (Ocampo et al., 2016; Mosteiro et al., 2016; Chiche et al., 2017, respectively) report crosstalk between reprogramming and senescence, providing insights on cellular plasticity in multicellular organisms.
Medical subject headings
- Cell Plasticity
- Cellular Reprogramming