Pericytes or Mesenchymal Stem Cells: Is That the Question?

Cano, Elena; Gebala, Véronique; Gerhardt, Holger · Cell Stem Cell · 2017

editorial · Level V

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Abstract

For almost a decade, mesenchymal stem cells (MSCs) were believed to reside as perivascular cells in vivo. In this issue of Cell Stem Cell, Guimarães-Camboa et al. (2017) challenge this idea and use lineage tracing to demonstrate that perivascular cells do not behave as tissue-specific progenitors in various organs, despite showing MSC potential in vitro.

Medical subject headings