Bringing a Leukemic Stem Cell Gene Signature into Clinics: Are We There Yet?

Richard-Carpentier, Guillaume; Sauvageau, Guy · Cell Stem Cell · 2017

editorial · Level V

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Abstract

Prognostic markers that capture leukemia stem cell (LSC) activity can be useful for the risk stratification of acute myeloid leukemia (AML) patients. In a recent issue of Nature, Ng et al. (2016) develop a prognostic score based on a 17-gene expression signature of LSCs to predict outcome in AML patients.

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