Precipitous Deterioration of Motor Function, Cognition, and Behavior.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 28264087.
- Also identified by DOI 10.1001/jamaneurol.2016.6159 and PMC identifier 5600817.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A 72-year-old woman developed new-onset depression, sustained an unexplained fall, and started walking cautiously. After 1 year, her depression resolved but she developed a dry cough. One year later, she experienced a more rapid decline in her gait with parkinsonism, visual difficulties with restricted vertical gaze, slowed horizontal and vertical saccades, dysphagia, apathy, and progressive cognitive decline, which led to her death 2 years later. The differential diagnosis, neuroimaging, and pathological findings are discussed, as well as their public health implications.
Medical subject headings
- Creutzfeldt-Jakob Syndrome
- Prion Proteins