Should I Stay or Should I Go: A Clash of α-Cell Identity.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28273469.
- Also identified by DOI 10.1016/j.cmet.2017.02.014.
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Abstract
Understanding mechanisms for maintaining pancreatic islet cell fate and function is important for addressing the urgent challenge of restoring islet β- and α-cell function in T1DM. In this issue of Cell Metabolism, Chakravarthy et al. (2017) identify a genetic mechanism by which mouse β-cells are spontaneously regenerated from adult α-cells.
Medical subject headings
- Glucagon-Secreting Cells
- Islets of Langerhans