Forecasting Fat Fibrosis.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28273471.
- Also identified by DOI 10.1016/j.cmet.2017.02.019.
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Abstract
Excess ECM and fibrosis of white adipose tissue (WAT) is associated with tissue dysfunction and type 2 diabetes. In this issue of Cell Metabolism, Marcelin et al. (2017) elucidate a key mechanism behind WAT fibrosis in which the activation of PDGFRα on adipocyte precursors drives this population toward a fibrotic phenotype.
Medical subject headings
- Adipose Tissue, White
- Diabetes Mellitus, Type 2