Inside the Chamber of Secrets of the Type III Secretion System.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28283066.
- Also identified by DOI 10.1016/j.cell.2017.02.028.
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Abstract
The bacterial type III secretion system is a specialized machine that injects effectors into eukaryotic cells to manipulate the host cell physiology. In this issue of Cell, Hu et al. use cryo-electron tomography to reveal an unprecedented level of details regarding the architecture of this machine and the conformational changes that occur during its assembly.
Medical subject headings
- Electron Microscope Tomography
- Type III Secretion Systems