Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28291788.
- Also identified by DOI 10.1371/journal.pmed.1002256 and PMC identifier 5349649.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
In a Perspective, David Bennett makes a case for neural reserve to be considered as a therapeutic endpoint in clinical trials for dementia.
Medical subject headings
- Alzheimer Disease
- Brain
- Cognitive Reserve
- Dementia
- Drug Discovery