On DNA numerical representations for genomic similarity computation.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 28323839.
- Also identified by DOI 10.1371/journal.pone.0173288 and PMC identifier 5360225.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Genomic signal processing (GSP) refers to the use of signal processing for the analysis of genomic data. GSP methods require the transformation or mapping of the genomic data to a numeric representation. To date, several DNA numeric representations (DNR) have been proposed; however, it is not clear what the properties of each DNR are and how the selection of one will affect the results when using a signal processing technique to analyze them. In this paper, we present an experimental study of the characteristics of nine of the most frequently-used DNR. The objective of this paper is to evaluate the behavior of each representation when used to measure the similarity of a given pair of DNA sequences.
Medical subject headings
- Sequence Analysis, DNA
- Signal Processing, Computer-Assisted