When TLRs fail, IgG has your back.
expert_opinion · Level V
Where this comes from
- Record sourced from PubMed, PMID 28330862.
- Also identified by DOI 10.1126/scitranslmed.aan0768.
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Abstract
Inherited TIRAP deficiency confers susceptibility to staphylococcal disease via impaired TLR2 and TLR4 responses, which can be rescued by bacteria-specific antibodies.
Medical subject headings
- Toll-Like Receptor 2
- Toll-Like Receptor 4