Operationalizing compensation over time in neurodegenerative disease.

Gregory, Sarah; Long, Jeffrey D; Klöppel, Stefan; Razi, Adeel; Scheller, Elisa; Minkova, Lora; Papoutsi, Marina; Mills, James A et al. · Brain · 2017

other · Level V

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Abstract

In pre-clinical Huntington's disease, normal behaviour is maintained despite neurodegeneration, suggesting a mechanism of compensation. Gregory, Long <i>et al</i>. present two mathematical models of compensation over time and their operationalisation for neuroimaging.

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