Effect of Tranexamic Acid on Transfusion Rates Following Total Joint Arthroplasty: A Cost and Comparative Effectiveness Analysis.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 28336035.
- Also identified by DOI 10.1016/j.ocl.2016.12.001.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Tranexamic acid (TXA) is used to reduce blood loss in orthopedic total joint arthroplasty (TJA). This study evaluates the effectiveness of TXA in reducing transfusions and hospital cost in TJA. Participants undergoing elective TJA were stratified into 2 cohorts: those not receiving and those receiving intravenous TXA. TXA decreased total hip arthroplasty (THA) transfusions from 22.7% to 11.9%, and total knee arthroplasty (TKA) from 19.4% to 7.0%. The average direct hospital cost reduction for THA and TKA was $3083 and $2582, respectively. Implementation of a TJA TXA protocol significantly reduced transfusions in a safe and cost-effective manner.
Medical subject headings
- Arthroplasty, Replacement, Hip
- Arthroplasty, Replacement, Knee
- Blood Loss, Surgical
- Blood Transfusion
- Tranexamic Acid
Anatomy
- hip
- knee