α<sub>S1</sub>-Casein elucidate major T-cell responses in cow's milk allergy.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 28343843.
- Also identified by DOI 10.1016/j.jaci.2017.02.028 and PMC identifier 5591766.
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Abstract
Cow’s milk allergy (CMA) is increasing in prevalence, affecting approximately 4% of children. Cow’s milk (CM) is a common cause of fatal/ near fatal anaphylactic reactions. Understanding of CM-specific CD4+ T-cells responses to milk allergens should help elucidate the pathological mechanisms of persistent CMA. Milk allergen epitopes specific T-cells were examined in CMA subjects. Frequencies and phenotypes of these T-cells were found to be different between older and younger subjects.
Medical subject headings
- Caseins
- Milk Hypersensitivity
- T-Lymphocytes