Purified Adipose-Derived Stromal Cells Provide Superior Fat Graft Retention Compared with Unenriched Stromal Vascular Fraction.

Zielins, Elizabeth R; Brett, Elizabeth A; Blackshear, Charles P; Flacco, John; Ransom, Ryan C; Longaker, Michael T; Wan, Derrick C · Plast Reconstr Surg · 2017

basic_science · Level V

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Abstract

Cell-assisted lipotransfer has shown much promise as a technique to improve fat graft retention in both mouse and human studies. However, the literature varies as to whether fresh stromal vascular fraction or culture-expanded adipose-derived stromal cells are used to augment volume retention. The authors' study sought to determine whether there was a significant advantage to using adipose-derived stromal cells over unpurified stromal vascular fraction cells in a mouse model of cell-assisted lipotransfer.

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