Cardiac regeneration: All work and no repair?

Kennedy-Lydon, Teresa; Rosenthal, Nadia · Sci Transl Med · 2017

review · Level V

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Abstract

Structural changes in the developing heart may influence the limited regenerative capacity of the adult heart. We examine how the workload exerted on the adult mammalian heart may limit regenerative capability and discuss recent therapies that demonstrate beneficial effects through unloading the heart.

Medical subject headings