Elevated levels of soluble humanleukocyte antigen-G in the airways are a marker for a low-inflammatory endotype of asthma.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 28363527.
- Also identified by DOI 10.1016/j.jaci.2017.02.031 and PMC identifier 5591772.
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Abstract
Soluble human leukocyte antigen-G (sHLA-G), an immunomodulatory molecule associated with suppression of inflammation, is elevated in the airways of asthmatic patients with a low inflammatory endotype as evidenced by low airway eosinophils and low exhaled nitric oxide.
Medical subject headings
- Asthma
- Bronchoalveolar Lavage Fluid
- HLA-G Antigens