biMM: efficient estimation of genetic variances and covariances for cohorts with high-dimensional phenotype measurements.
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- Record sourced from PubMed, PMID 28369165.
- Also identified by DOI 10.1093/bioinformatics/btx166 and PMC identifier 5860115.
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Abstract
SUMMARY: Genetic research utilizes a decomposition of trait variances and covariances into genetic and environmental parts. Our software package biMM is a computationally efficient implementation of a bivariate linear mixed model for settings where hundreds of traits have been measured on partially overlapping sets of individuals. AVAILABILITY AND IMPLEMENTATION: Implementation in R freely available at www.iki.fi/mpirinen . CONTACT: matti.pirinen@helsinki.fi. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
Medical subject headings
- Genetic Variation
- Genetics, Population
- Models, Statistical
- Software