Narrow-band imaging in transoral laser surgery for early glottic cancer in relation to clinical outcome.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 28370672.
- Also identified by DOI 10.1002/hed.24773.
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Abstract
The purpose of this study was to validate the prognostic value of adding narrow-band imaging (NBI) during transoral laser surgery (TLS) for early glottic cancer. In 84 patients, 93 transoral laser resections were performed for carcinoma in situ (Tcis), T1, or T2 glottic cancer. TLS was preceded by intraoperative evaluation using traditional white-light imaging (WLI) in 51 cases. In 42 cases, NBI was used in addition to WLI. Local recurrence rate and recurrence-free survival were retrospectively compared between both groups. Local recurrences developed in 14% of the 93 cases: 12 of 51 patients (24%) were treated by TLS based on WLI alone, and in 1 of 42 patients (2%) in the NBI group (P < .01). Two-year recurrence-free survival was 82% in the WLI group and 98% in the NBI group (P < .05). Additional use of NBI during TLS for early glottic cancer significantly improves clinical outcome.
Medical subject headings
- Glottis
- Laryngeal Neoplasms
- Laser Therapy
- Monitoring, Intraoperative
- Narrow Band Imaging
- Natural Orifice Endoscopic Surgery