Specific Polysaccharide Antibody Deficiency Revealed by Severe Bacterial Infections in Adulthood: A Report on 11 Cases.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 28379361.
- Also identified by DOI 10.1093/cid/cix284.
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Abstract
We report on 11 cases of specific polysaccharide antibody deficiency (SPAD) revealed in adulthood by severe infections with encapsulated bacteria. Given that immunoglobulin replacement therapy can effectively prevent the recurrence of bacterial infections in this context, SPAD should be considered once other antibody deficiencies have been ruled out.
Medical subject headings
- Antibodies, Bacterial
- Bacterial Infections
- Immunologic Deficiency Syndromes
- Polysaccharides, Bacterial