The effect of continuous intrathecal baclofen therapy on ambulatory children with cerebral palsy.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 28379909.
- Also identified by DOI 10.1097/BPB.0000000000000462.
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Abstract
The effect of a continuous intrathecal infusion of baclofen (CITB) was retrospectively studied in 19 ambulatory children with cerebral palsy (aged 12.4±4.9 years at CITB initiation). The mean clinical follow-up was 5.1±2.4 years and the mean follow-up gait analysis was 2.8±1.9 years. Spastic cerebral palsy diagnosis [14 (74%)] was most frequent. Most patients [11 (58%)] were Gross Motor Function Classification System level III. CITB significantly improved muscle tone and knee flexion at initial contact (P<0.05), but it did not lead to improved gait speed or gross motor function.
Medical subject headings
- Baclofen
- Cerebral Palsy
- Muscle Relaxants, Central
- Walking