Drosophilosophical: Re-thinking Adaptive Immunity in the Fly.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28388404.
- Also identified by DOI 10.1016/j.cell.2017.03.032.
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Abstract
For decades, flies have been a model for innate immunity. In this issue of Cell, Tassetto et al. describe a mechanism for antiviral RNAi spreading that parallels mammalian adaptive immunity through reverse-transcribed vDNA circles and the systemic dissemination of small-RNA-containing exosomes.
Medical subject headings
- Adaptive Immunity
- RNA Interference