DEAD-Box RNA Binding Protein DDX5: Not a Black-Box during Reprogramming.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28388421.
- Also identified by DOI 10.1016/j.stem.2017.03.006.
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Abstract
The role of RNA binding proteins (RBPs) during nuclear reprogramming is poorly characterized. In this issue of Cell Stem Cell,Li et al. (2017) show that DEAD-box RBP DDX5 acts as a reprogramming roadblock and give important mechanistic insights into the establishment of pluripotency by characterizing the intricate downstream events.
Medical subject headings
- DEAD-box RNA Helicases
- RNA-Binding Proteins