Current Status of Dengue Therapeutics Research and Development.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 28403438.
- Also identified by DOI 10.1093/infdis/jiw423 and PMC identifier 5388029.
- Licence recorded as CC BY-NC-ND.
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Abstract
Dengue is a significant global health problem. Even though a vaccine against dengue is now available, which is a notable achievement, its long-term protective efficacy against each of the 4 dengue virus serotypes remains to be definitively determined. Consequently, drugs directed at the viral targets or critical host mechanisms that can be used safely as prophylaxis or treatment to effectively ameliorate disease or reduce disease severity and fatalities are still needed to reduce the burden of dengue. This review will provide a brief account of the status of therapeutics research and development for dengue.
Medical subject headings
- Antibodies, Monoclonal
- Antiviral Agents
- Dengue