Spermidine Promotes Cardioprotective Autophagy.

Tong, Dan; Hill, Joseph A · Circ Res · 2017

review · Level V

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Abstract

A recent study published in <i>Nature Medicine</i> reports that dietary supplementation with spermidine, a natural polyamine, extends life span and reverses aging-associated cardiac dysfunction in mice through induction of autophagy. Similar protective effects of spermidine on human cardiovascular health were also suggested by epidemiological studies.

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