Repurposing QuantiFERON for Detection of Neutralizing Interferon-γ Autoantibodies in Patients With Nontuberculous Mycobacterial Infections.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 28430999.
- Also identified by DOI 10.1093/cid/cix372.
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Abstract
Nontuberculous mycobacterial infections due to autoantibodies targeting interferon-γ are an emerging medical problem. However, case finding is hampered due to highly complex diagnostic procedures not available in routine laboratories. We show that QuantiFERON assays can be exploited as a simple screening tool that may facilitate adequate and timely treatment.
Medical subject headings
- Antibodies, Neutralizing
- Autoantibodies
- Interferon-gamma
- Interferon-gamma Release Tests
- Mycobacterium Infections, Nontuberculous