Congenital Zika Virus Infection Induces Severe Spinal Cord Injury.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 28444144.
- Also identified by DOI 10.1093/cid/cix374.
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Abstract
We report 2 fatal cases of congenital Zika virus (ZIKV) infection. Brain anomalies, including atrophy of the cerebral cortex and brainstem, and cerebellar aplasia were observed. The spinal cord showed architectural distortion, severe neuronal loss, and microcalcifications. The ZIKV proteins and flavivirus-like particles were detected in cytoplasm of spinal neurons, and spinal cord samples were positive for ZIKV RNA.
Medical subject headings
- Pregnancy Complications, Infectious
- Spinal Cord
- Spinal Cord Diseases
- Zika Virus
- Zika Virus Infection