Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses.
Level III
Where this comes from
- Record sourced from PubMed, PMID 28453839.
- Also identified by DOI 10.1093/infdis/jix046 and PMC identifier 5407053.
- Licence recorded as CC BY-NC-ND.
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Abstract
The World Health Organization (WHO) published 2 alcohol-based formulations to be used in healthcare settings and for outbreak-associated infections, but inactivation efficacies of these products have not been determined against (re-)emerging viruses. In this study, we evaluated the virucidal activity of these WHO products in a comparative analysis. Zika virus (ZIKV), Ebola virus (EBOV), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV) as (re-)emerging viral pathogens and other enveloped viruses could be efficiently inactivated by both WHO formulations, implicating their use in healthcare systems and viral outbreak situations.
Medical subject headings
- Antisepsis
- Ebolavirus
- Hand Hygiene
- Middle East Respiratory Syndrome Coronavirus
- Severe acute respiratory syndrome-related coronavirus
- Zika Virus