When Size Matters: How Astrocytic Processes Shape Metabolism.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28467945.
- Also identified by DOI 10.1016/j.cmet.2017.04.016.
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Abstract
The hypothalamic control of metabolism appears to be a puzzle that cannot be explained by neuronal function alone. Zhang and colleagues (2017) add a few new pieces by demonstrating that astrocytes critically modulate neural circuits controlling energy homeostasis through nutritional-status-dependent morphological plasticity and IKKβ/NF-κB signaling, which modulate extracellular neurotransmitter bioavailability.
Medical subject headings
- Astrocytes
- Hypothalamus
- I-kappa B Kinase
- NF-kappa B
- Signal Transduction