Nociceptive brain activity as a measure of analgesic efficacy in infants.
Where this comes from
- Record sourced from PubMed, PMID 28469039.
- Also identified by DOI 10.1126/scitranslmed.aah6122 and PMC identifier 5884430.
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Abstract
Pain in infants is undertreated and poorly understood, representing a major clinical problem. In part, this is due to our inability to objectively measure pain in nonverbal populations. We present and validate an electroencephalography-based measure of infant nociceptive brain activity that is evoked by acute noxious stimulation and is sensitive to analgesic modulation. This measure should be valuable both for mechanistic investigations and for testing analgesic efficacy in the infant population.
Medical subject headings
- Analgesics
- Pain