Synthetic Embryos: Windows into Mammalian Development.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28475880.
- Also identified by DOI 10.1016/j.stem.2017.04.001.
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Abstract
Mammalian embryonic stem cells (ESCs) can self-organize in vitro, but whether they can recreate early embryonic morphogenesis is unclear. Harrison et al. recently demonstrate in Science that 3D co-cultures of mouse ESCs and trophoblast stem cells self-organize into embryo-like structures that recreate many features of early mouse development.
Medical subject headings
- Embryo, Mammalian
- Embryonic Stem Cells