Large-field-of-view imaging by multi-pupil adaptive optics.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28481364.
- Also identified by DOI 10.1038/nmeth.4290 and PMC identifier 5482233.
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Abstract
Adaptive optics can correct for optical aberrations. We developed multi-pupil adaptive optics (MPAO), which enables simultaneous wavefront correction over a field of view of 450 × 450 μm<sup>2</sup> and expands the correction area to nine times that of conventional methods. MPAO's ability to perform spatially independent wavefront control further enables 3D nonplanar imaging. We applied MPAO to in vivo structural and functional imaging in the mouse brain.
Medical subject headings
- Brain
- Image Enhancement
- Imaging, Three-Dimensional
- Lenses
- Microscopy, Fluorescence