Concordance Between Anal and Oral Human Papillomavirus Infections Among Young Men Who have Sex With Men.

Steinau, Martin; Gorbach, Pamina; Gratzer, Beau; Braxton, Jim; Kerndt, Peter R; Crosby, Richard A; Unger, Elizabeth R; Markowitz, Lauri E et al. · J Infect Dis · 2017

cross_sectional · Level IV

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Abstract

Prevalence of human papillomavirus (HPV) infections was assessed among 1033 young men who have sex with men (MSM) aged 18-26 years. HPV (any type) was detected in 742 (71.8%) anal specimens and 101 (9.8%) oral specimens. Although HPV was detected in specimens from both anatomical sites in 83 (8.0%) participants, type-specific concordance for at least 1 HPV type was found in only 35 (3.4%) participants. HIV and smoking were associated with higher prevalence at both sites and frequency of concordant types. Coinfections of identical HPV types were rare, suggesting independent infection events and/or different modes of clearance.

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