Infectivity of Post-Kala-azar Dermal Leishmaniasis Patients to Sand Flies: Revisiting a Proof of Concept in the Context of the Kala-azar Elimination Program in the Indian Subcontinent.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 28520851.
- Also identified by DOI 10.1093/cid/cix245 and PMC identifier 5848257.
- Licence recorded as CC BY-NC-ND.
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Abstract
We compared xenodiagnosis with quantitative polymerase chain reaction in skin biopsies from 3 patients with maculopapular or nodular post-kala-azar dermal leishmaniasis (PKDL). All patients infected sand flies. Parasite loads in skin varied from 1428 to 63 058 parasites per microgram. PKDL detection and treatment are important missing components of the kala-azar elimination program.
Medical subject headings
- Leishmania donovani
- Leishmaniasis, Visceral
- Psychodidae