Irradiation in a flash: Unique sparing of memory in mice after whole brain irradiation with dose rates above 100Gy/s.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28545957.
- Also identified by DOI 10.1016/j.radonc.2017.05.003.
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Abstract
This study shows for the first time that normal brain tissue toxicities after WBI can be reduced with increased dose rate. Spatial memory is preserved after WBI with mean dose rates above 100Gy/s, whereas 10Gy WBI at a conventional radiotherapy dose rate (0.1Gy/s) totally impairs spatial memory.
Medical subject headings
- Brain
- Cranial Irradiation
- Memory
- Radiation Injuries, Experimental