Gut Microbiota: Potential for a Unifying Hypothesis for Prevention and Treatment of Hypertension.

Qi, YanFei; Kim, Seungbum; Richards, Elaine M; Raizada, Mohan K; Pepine, Carl J · Circ Res · 2017

review · Level V

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Abstract

Despite major advances in pharmacological and device-based therapies, systemic hypertension (HTN) continues to be the major, modifiable risk factor for most cardiovascular disease and a leading cause of morbidity and mortality. Treatment resistant HTN (RH) is present in ≈15% to 20% of hypertensive patients, with few treatment options. These facts provide an opportunity to develop novel hypotheses to advance this field.

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