CWDPRNP: a tool for cervid prion sequence analysis in program R.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28549074.
- Also identified by DOI 10.1093/bioinformatics/btx333.
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Abstract
Chronic wasting disease is a fatal, neurological disease caused by an infectious prion protein, which affects economically and ecologically important members of the family Cervidae. Single nucleotide polymorphisms within the prion protein gene have been linked to differential susceptibility to the disease in many species. Wildlife managers are seeking to determine the frequencies of disease-associated alleles and genotypes and delineate spatial genetic patterns. The CWDPRNP package, implemented in program R, provides a unified framework for analyzing prion protein gene variability and spatial structure. The CWDPRNP package, manual and example data files are available at http://ecosystems.psu.edu/research/labs/walter-lab/additional-labs/population-genetics-lab. This package is available for all commonly used platforms. wlm159psu@gmail.com.
Medical subject headings
- Deer
- Prions
- Sequence Analysis, DNA
- Software
- Wasting Disease, Chronic