Vancomycin Taper and Risk of Failure of Fecal Microbiota Transplantation in Patients With Recurrent Clostridium difficile Infection.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 28575220.
- Also identified by DOI 10.1093/cid/cix511.
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Abstract
We retrospectively analyzed a cohort of 109 subjects treated for recurrent Clostridium difficile infection with fecal microbiota transplantation (FMT) at a tertiary referral center between 2011 and 2014 to determine risk factors for FMT failure. In a multivariate analysis, failure to use an oral vancomycin taper preceding FMT was associated with a significant risk of FMT failure (odds ratio, 0.15; 95% confidence interval, .007-.40).
Medical subject headings
- Anti-Bacterial Agents
- Clostridioides difficile
- Clostridium Infections
- Feces
- Vancomycin