Durability of Response After Hepatitis B Surface Antigen Seroclearance During Nucleos(t)ide Analogue Treatment in a Multiethnic Cohort of Chronic Hepatitis B Patients: Results After Treatment Cessation.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 28575292.
- Also identified by DOI 10.1093/cid/cix353.
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Abstract
In 70 chronic hepatitis B patients with hepatitis B surface antigen seroclearance during nucleos(t)ide analogue therapy, response was sustained in all 54 patients who discontinued treatment. Clinically significant relapses as indicated by high hepatitis B virus DNA and ALT levels were not observed. Anti-HBs positivity may not be required to ensure sustained off-treatment response.
Medical subject headings
- Antiviral Agents
- Hepatitis B Antigens
- Hepatitis B, Chronic
- Sustained Virologic Response