Advances in Therapeutic Approaches to Extend Healthspan: a perspective from the 2<sup>nd</sup> Scripps Symposium on the Biology of Aging.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28585366.
- Also identified by DOI 10.1111/acel.12620 and PMC identifier 5506446.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The 2<sup>nd</sup> Scripps Florida Symposium on The Biology of Aging entitled 'Advances in Therapeutic Approaches to Extend Healthspan' was held on January 22<sup>nd</sup> -25<sup>th</sup> , 2017 at The Scripps Research Institute in Jupiter, Florida. The meeting highlighted a variety of therapeutic approaches in animal models of aging that either are or soon will be in clinic trials. For example, drugs targeting senescent cells, metformin, rapalogs, NAD precursors, young plasma, mitochondrial-targeted free radical scavengers, stem cells, and stem cell factors all have shown significant preclinical efficacy. This perspective, based on presentations and discussions at the symposium, outlines the current and future state of development of therapeutic approaches to extend human healthspan.
Medical subject headings
- Cellular Senescence
- Free Radical Scavengers
- Longevity
- Stem Cell Transplantation