Vancomycin Taper and Pulse Regimen With Careful Follow-up for Patients With Recurrent Clostridium difficile Infection.

Sirbu, Benjamin D; Soriano, Melinda M; Manzo, Carl; Lum, Jessica; Gerding, Dale N; Johnson, Stuart · Clin Infect Dis · 2017

retrospective_cohort · Level III

Where this comes from

Abstract

We retrospectively studied vancomycin taper and pulse treatment on 100 consecutive, evaluable patients with recurrent Clostridium difficile infection. Following taper to once-daily vancomycin dosing, 22 of 36 patients (61%) who received every-other-day dosing (QOD) and 50 of 64 (81%) who received QOD followed by every-third-day dosing were cured (P = .03).

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