Improvement in Renal Cystic Disease of Tuberous Sclerosis Complex After Treatment with Mammalian Target of Rapamycin Inhibitor.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 28600153.
- Also identified by DOI 10.1016/j.jpeds.2017.05.015.
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Abstract
Renal cysts occur in approximately 50% of patients with tuberous sclerosis complex, but their clinical significance and response to treatment are unknown. Abdominal imaging of 15 patients with tuberous sclerosis complex-associated renal cystic disease who had received mammalian target of rapamycin inhibitor therapy for other tuberous sclerosis complex-related indications was evaluated. Reductions in cyst number, sum diameter, and volume were observed.
Medical subject headings
- Immunosuppressive Agents
- Kidney Diseases, Cystic
- Sirolimus
- Tuberous Sclerosis