Just a Spoonful of Sugar Helps the Tolerance Go Up.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28622502.
- Also identified by DOI 10.1016/j.cell.2017.05.040.
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Abstract
Survival of deleterious infections depends significantly on how much stress the affected organism can tolerate. In this issue, Weis et al. find that mice can survive sepsis by maintaining normoglycemia through ferritin's capacity to inactivate Fe<sup>2+</sup> ions that otherwise induce free radicals impacting gluconeogenesis in the liver.
Medical subject headings
- Gluconeogenesis
- Immune Tolerance