Direct Stimulation of Cardiogenesis: A New Paradigm for Treating Heart Disease.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 28642324.
- Also identified by DOI 10.1161/CIRCRESAHA.117.311062 and PMC identifier 5545096.
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Abstract
Heart failure is highly prevalent and is associated with substantial mortality and morbidity, despite the many treatment options currently available. We propose a potential new approach to treating heart disease: promoting cardiogenesis from existing cardiac myocytes by inhibiting the Hippo pathway, a “stop growth” pathway in the heart.
Medical subject headings
- Heart
- Heart Diseases
- Organogenesis
- Protein Serine-Threonine Kinases