Pro- versus Anti-inflammatory Actions of HDLs in Innate Immunity.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28648980.
- Also identified by DOI 10.1016/j.cmet.2017.04.007.
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Abstract
High-density lipoproteins (HDLs) can inhibit inflammatory cytokine expression on innate immune cells, but sometimes they promote cytokine production as suggested in a recent article in Cell Metabolism by van der Vorst et al. (2017). Kopecky et al. point out that the origin, handling, and storage conditions of HDL preparations dictate their functional properties and can specifically affect immune cells to evoke a pro-inflammatory response.
Medical subject headings
- Immunity, Innate
- Lipoproteins, HDL