Building bridges between cellular and molecular structural biology.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 28682240.
- Also identified by DOI 10.7554/eLife.25835 and PMC identifier 5524535.
- Licence recorded as CC0.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The integration of cellular and molecular structural data is key to understanding the function of macromolecular assemblies and complexes in their in vivo context. Here we report on the outcomes of a workshop that discussed how to integrate structural data from a range of public archives. The workshop identified two main priorities: the development of tools and file formats to support segmentation (that is, the decomposition of a three-dimensional volume into regions that can be associated with defined objects), and the development of tools to support the annotation of biological structures.
Medical subject headings
- Cell Biology
- Computational Biology
- Macromolecular Substances