Energy Sparing Orexigenic Inflammation of Obesity.
Where this comes from
- Record sourced from PubMed, PMID 28683278.
- Also identified by DOI 10.1016/j.cmet.2017.06.013.
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Abstract
The neuro-immune interactions that integrate host metabolism in health and disease are unclear. A new study by Valdearcos et al. (2017) describes how sensing of high-fat diet by microglia, brain's resident innate immune cells, recruits additional bone-marrow-derived myeloid cells into the hypothalamus to produce inflammation and cause weight gain.
Medical subject headings
- Diet, High-Fat
- Energy Metabolism
- Inflammation
- Microglia
- Myeloid Cells
- Obesity