Is Glycogenin Essential for Glycogen Synthesis?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28683279.
- Also identified by DOI 10.1016/j.cmet.2017.06.017.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Glycogen synthesis requires a priming oligosaccharide, formed by autoglucosylation of glycogenin, a core protein in glycogen particles. In this edition of Cell Metabolism, Testoni et al. (2017) challenge this generally accepted concept by demonstrating that glycogenin inactivation in mice results in an increased amount of glycogen and not glycogen depletion.
Medical subject headings
- Glucosyltransferases
- Glycogen
- Glycoproteins